We can understand more about suffering and ignorance by considering the first of the Dom-pa bash, the Four Statements that summarize the Buddha’s teachings:
All compounded things are impermanent.
Applying this statement to ourselves and our own situation requires special effort, since we seem to go on in the same way from day to day and year to year.
Of course, we will admit there have been changes, but ‘we’ are the same – the child, the adult, the old man or woman are all ‘me’.
The evidence of impermanence is right before us, in the changing of each moment of experience in this ever-changing realm, but our vision is not attuned to its manifestations.
Tarthang Tulku Rinpoche Milking the Painted Cow